Wang Lab »  Publications
Wang Lab »  Publications


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Nielsen CM, Huang L, Murphy PA, Lawton MT, Wang RA
Mouse Models of Cerebral Arteriovenous Malformation.
Stroke; a journal of cerebral circulation, Jan-2016;47(1):293-300.  Epub 2015 Sep 8.
Murphy PA, Kim TN, Huang L, Nielsen CM, Lawton MT, Adams RH, Schaffer CB, Wang RA
Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels.
Proceedings of the National Academy of Sciences of the United States of America, Dec-16-2014;111(50):18007-12.  Epub 2014 Dec 2.
Lin Y, Jiang W, Ng J, Jina A, Wang RA
Endothelial ephrin-B2 is essential for arterial vasodilation in mice.
Microcirculation (New York, N.Y. : 1994), Oct-2014;21(7):578-86.
Nielsen CM, Cuervo H, Ding VW, Kong Y, Huang EJ, Wang RA
Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.
Development (Cambridge, England), Oct-2014;141(19):3782-92.  Epub 2014 Sep 10.
Lindskog H, Kim YH, Jelin EB, Kong Y, Guevara-Gallardo S, Kim TN, Wang RA
Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.
Development (Cambridge, England), Mar-2014;141(5):1120-8.
Costa MJ, Wu X, Cuervo H, Srinivasan R, Bechis SK, Cheang E, Marjanovic O, Gridley T, Cvetic CA, Wang RA
Notch4 is required for tumor onset and perfusion.
Vascular cell, 2013;[epublish]5(1):7.
Murphy PA, Kim TN, Lu G, Bollen AW, Schaffer CB, Wang RA
Notch4 normalization reduces blood vessel size in arteriovenous malformations.
Science translational medicine, Jan-18-2012;4(117):117ra8.
Clever JL, Sakai Y, Wang RA, Schneider DB
Inefficient skeletal muscle repair in inhibitor of differentiation knockout mice suggests a crucial role for BMP signaling during adult muscle regeneration.
American journal of physiology. Cell physiology, May-2010;298(5):C1087-99.  Epub 2010 Feb 24.
Miniati D, Jelin EB, Ng J, Wu J, Carlson TR, Wu X, Looney MR, Wang RA
Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice.
American journal of physiology. Lung cellular and molecular physiology, Feb-2010;298(2):L169-77.  Epub 2009 Nov 20.
Herbert SP, Huisken J, Kim TN, Feldman ME, Houseman BT, Wang RA, Shokat KM, Stainier DY
Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation.
Science (New York, N.Y.), Oct-9-2009;326(5950):294-8.
Murphy PA, Lu G, Shiah S, Bollen AW, Wang RA
Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.
Laboratory investigation; a journal of technical methods and pathology, Sep-2009;89(9):971-82.  Epub 2009 Jun 22.
Yang Y, Tang G, Yan J, Park B, Hoffman A, Tie G, Wang R, Messina LM
Cellular and molecular mechanism regulating blood flow recovery in acute versus gradual femoral artery occlusion are distinct in the mouse.
Journal of vascular surgery, Dec-2008;48(6):1546-58.
Kim YH, Hu H, Guevara-Gallardo S, Lam MT, Fong SY, Wang RA
Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis.
Development (Cambridge, England), Nov-2008;135(22):3755-64.
Murphy PA, Lam MT, Wu X, Kim TN, Vartanian SM, Bollen AW, Carlson TR, Wang RA
Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice.
Proceedings of the National Academy of Sciences of the United States of America, Aug-5-2008;105(31):10901-6.  Epub 2008 Jul 30.
He C, Hu H, Braren R, Fong SY, Trumpp A, Carlson TR, Wang RA
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo.
Development (Cambridge, England), Aug-2008;135(14):2467-77.  Epub 2008 Jun 11.
Dubois NC, Adolphe C, Ehninger A, Wang RA, Robertson EJ, Trumpp A
Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function.
Development (Cambridge, England), Aug-2008;135(14):2455-65.  Epub 2008 Jun 11.
Carlson TR, Hu H, Braren R, Kim YH, Wang RA
Cell-autonomous requirement for beta1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice.
Development (Cambridge, England), Jun-2008;135(12):2193-202.  Epub 2008 May 14.
Tward AD, Jones KD, Yant S, Cheung ST, Fan ST, Chen X, Kay MA, Wang R, Bishop JM
Distinct pathways of genomic progression to benign and malignant tumors of the liver.
Proceedings of the National Academy of Sciences of the United States of America, Sep-11-2007;104(37):14771-6.  Epub 2007 Sep 4.
Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, Wang R
Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.
The Journal of cell biology, Jan-2-2006;172(1):151-62.
Yan J, Tang GL, Wang R, Messina LM
Optimization of adenovirus-mediated endothelial nitric oxide synthase delivery in rat hindlimb ischemia.
Gene therapy, Nov-2005;12(22):1640-50.
Proctor JM, Zang K, Wang D, Wang R, Reichardt LF
Vascular development of the brain requires beta8 integrin expression in the neuroepithelium.
The Journal of neuroscience : the official journal of the Society for Neuroscience, Oct-26-2005;25(43):9940-8.
Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ, Messina LM, Capobianco AJ, Werb Z, Wang R
Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice.
Proceedings of the National Academy of Sciences of the United States of America, Jul-12-2005;102(28):9884-9.  Epub 2005 Jun 30.
Carpenter B, Lin Y, Stoll S, Raffai RL, McCuskey R, Wang R
VEGF is crucial for the hepatic vascular development required for lipoprotein uptake.
Development (Cambridge, England), Jul-2005;132(14):3293-303.  Epub 2005 Jun 8.
Tang GL, Chang DS, Sarkar R, Wang R, Messina LM
The effect of gradual or acute arterial occlusion on skeletal muscle blood flow, arteriogenesis, and inflammation in rat hindlimb ischemia.
Journal of vascular surgery, Feb-2005;41(2):312-20.
Tang G, Charo DN, Wang R, Charo IF, Messina L
CCR2-/- knockout mice revascularize normally in response to severe hindlimb ischemia.
Journal of vascular surgery, Oct-2004;40(4):786-95.
Chang DS, Su H, Tang GL, Brevetti LS, Sarkar R, Wang R, Kan YW, Messina LM
Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb.
Molecular therapy : the journal of the American Society of Gene Therapy, Jan-2003;7(1):44-51.
Wang R, Ferrell LD, Faouzi S, Maher JJ, Bishop JM
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice.
The Journal of cell biology, May-28-2001;153(5):1023-34.
Wang R, Kobayashi R, Bishop JM
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor.
Proceedings of the National Academy of Sciences of the United States of America, Aug-6-1996;93(16):8425-30.
Wang R, Siegal GP, Scott DL, Bautch VL
Developmental analysis of bone tumors in polyomavirus transgenic mice.
Laboratory investigation; a journal of technical methods and pathology, Jan-1994;70(1):86-94.
Wang R, Clark R, Bautch VL
Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development.
Development (Cambridge, England), Feb-1992;114(2):303-16.
Dubois NA, Kolpack LC, Wang R, Azizkhan RG, Bautch VL
Isolation and characterization of an established endothelial cell line from transgenic mouse hemangiomas.
Experimental cell research, Oct-1991;196(2):302-13.
Wang R, Bautch VL
The polyomavirus early region gene in transgenic mice causes vascular and bone tumors.
Journal of virology, Oct-1991;65(10):5174-83.
[Determination of metabolites of prostacyclin and thromboxane A2 in the endometrium in normal women and patients with metrorrhagia].
Zhonghua fu chan ke za zhi, Jan-1988;23(1):38-41, 61-2.